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Take this medication by mouthusually once a day at bedtime or as directed by your doctorIf you have trouble swallowing the pillstake with a full glass of water while standing upFollow the dosing schedule carefullyAsk your doctor if you have any questionsThe dosage is based on your medical condition and response to therapy.

International Agency for Research on CancerIARCV.61974IARC V.211979K.SLarrson and DMachinSafety requirements for contraceptive steroidsFMichaledCambridge University PressCambridgepp30-2691989Sixth Annual Report on Carcinogens V.2pp 693-6961991MedSciRes198715:703-704JohnstoneE.Eand FranklinR.R1964Assay of progestins for fetal virilizing properties using the mouseObstet Gynecol23:359-62SeegmillerR.ENelsonG.Wand JohnsonC.K1983Evaluation of the teratogenic potential of Delalutin17-hydroxyprogesterone caproatein miceTeratology 28:201-8SuchowskyG.Kand JunkmannK1961A study of the virilizing effects of progesterone on the female rat fetusEndocrinolgy 68:341-9ScholerH.F.Land de WachterA.M1961Evaluation of androgenic properties of progestational compounds in the rat by the female foetal masculinization testActaEndocrinol38:128-36HudsonRPharrissB.BTillsonS.Aand RenoF1978Preclinical evaluation of intrauterine progesterone as a contraceptive agentIIIEmbryology and toxicologyContraception 17:489-97FooteW.DFooteW.Cand FooteL.H1968Influence of certain natural and synthetic steroids on genital development in guinea pigsFertilSteril19:606-15WhartonL.RJrand ScottR.B1964Experimental production of genital lessions with norethindroneAm JObstetGynecol89:701-15 ScialliA.R1988Developmental effects of progesterone and its derivativesReproductive Toxicol2:3-11.

Every effort has been made to ensure that the information provided by Cerner MultumIncMultumis accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveMultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseMultum’s drug information does not endorse drugsdiagnose patients or recommend therapyMultum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safeeffective or appropriate for any given patientMultum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum providesThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have questions about the drugs you are takingcheck with your doctornurse or pharmacist.

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